A conference, Progress on Statistical Issues in Searches, will take place at SLAC, Stanford, California, on 4–6 June 2012. It will deal with statistical issues that arise in experiments searching for new phenomena. The participation of practitioners of particle physics, astrophysics, cosmology, photon science (research using high-intensity X-ray beams for structural studies) and statistics is intended to foster mutual exchanges of ideas and experience, identify open problems, and promote collaborative research. Further details can be found at www-conf.slac.stanford.edu/statisticalissues2012/.